STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANU13068.1Riboflavin biosynthesis protein RibD; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.865
ANU13067.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
    0.690
ANU12799.1
Bifunctional folylpolyglutamate synthase/dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.560
ANU13066.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.550
ANU14946.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.536
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
  
 0.530
ANU13801.1
CsbD family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0337 (CsbD) family.
   
    0.525
ANU14158.1
General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.525
ANU15121.1
RNA polymerase sigma factor SigB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family.
   
    0.525
ANU13244.1
Sugar epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.520
Your Current Organism:
Planococcus halocryophilus
NCBI taxonomy Id: 1215089
Other names: DSM 24743, JCM 17719, P. halocryophilus, Planococcus halocryophilus Mykytczuk et al. 2012, strain Or1
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