AGA65277.1 protein (Liberibacter crescens) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AGA65277.1

Flp pilus assembly protein RcpC/CpaB. (266 aa)

Predicted Functional Partners:

AGA65276.1

0.986

AGA65272.1

0.984

AGA65274.1

0.979

AGA65278.1

0.979

AGA65271.1

0.978

AGA65273.1

0.959

AGA65068.1

0.907

AGA65275.1

0.891

AGA65067.1

0.794

AGA65134.1

0.792

Your Current Organism:

Liberibacter crescens

NCBI taxonomy Id: 1215343
Other names: L. crescens BT-1, Liberibacter crescens BT-1, Liberibacter sp. BT-1, bacterium BT-1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGA65067.1	AGA65068.1	B488_10750	B488_10760	Putative transmembrane protein.	Hypothetical protein.	0.949
AGA65067.1	AGA65134.1	B488_10750	B488_11420	Putative transmembrane protein.	Flp pilus assembly protein TadD, contains TPR repeat.	0.767
AGA65067.1	AGA65271.1	B488_10750	B488_12790	Putative transmembrane protein.	Type II/IV secretion system protein TadC, Flp pilus assembly.	0.488
AGA65067.1	AGA65272.1	B488_10750	B488_12800	Putative transmembrane protein.	Flp pilus assembly protein TadB.	0.474
AGA65067.1	AGA65274.1	B488_10750	B488_12820	Putative transmembrane protein.	Type II/IV secretion system ATPase TadZ/CpaE, Flp pilus assembly.	0.845
AGA65067.1	AGA65275.1	B488_10750	B488_12830	Putative transmembrane protein.	Components of type IV pilus.	0.781
AGA65067.1	AGA65276.1	B488_10750	B488_12840	Putative transmembrane protein.	Type II/IV secretion system secretin RcpA/CpaC, Flp pilus assembly; Belongs to the bacterial secretin family.	0.517
AGA65067.1	AGA65277.1	B488_10750	B488_12850	Putative transmembrane protein.	Flp pilus assembly protein RcpC/CpaB.	0.794
AGA65067.1	AGA65278.1	B488_10750	B488_12860	Putative transmembrane protein.	Prepilin peptidase CpaA.	0.804
AGA65068.1	AGA65067.1	B488_10760	B488_10750	Hypothetical protein.	Putative transmembrane protein.	0.949
AGA65068.1	AGA65134.1	B488_10760	B488_11420	Hypothetical protein.	Flp pilus assembly protein TadD, contains TPR repeat.	0.799
AGA65068.1	AGA65271.1	B488_10760	B488_12790	Hypothetical protein.	Type II/IV secretion system protein TadC, Flp pilus assembly.	0.692
AGA65068.1	AGA65272.1	B488_10760	B488_12800	Hypothetical protein.	Flp pilus assembly protein TadB.	0.788
AGA65068.1	AGA65273.1	B488_10760	B488_12810	Hypothetical protein.	Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily.	0.615
AGA65068.1	AGA65274.1	B488_10760	B488_12820	Hypothetical protein.	Type II/IV secretion system ATPase TadZ/CpaE, Flp pilus assembly.	0.954
AGA65068.1	AGA65275.1	B488_10760	B488_12830	Hypothetical protein.	Components of type IV pilus.	0.778
AGA65068.1	AGA65276.1	B488_10760	B488_12840	Hypothetical protein.	Type II/IV secretion system secretin RcpA/CpaC, Flp pilus assembly; Belongs to the bacterial secretin family.	0.610
AGA65068.1	AGA65277.1	B488_10760	B488_12850	Hypothetical protein.	Flp pilus assembly protein RcpC/CpaB.	0.907
AGA65068.1	AGA65278.1	B488_10760	B488_12860	Hypothetical protein.	Prepilin peptidase CpaA.	0.840
AGA65134.1	AGA65067.1	B488_11420	B488_10750	Flp pilus assembly protein TadD, contains TPR repeat.	Putative transmembrane protein.	0.767

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.909

expected number of edges:

23

PPI enrichment p-value:

0.00171

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006366

Transcription by RNA polymerase II

5 of 77

1.6

1.53

0.00030

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005665

RNA polymerase II, core complex

4 of 12

2.31

2.73

4.99e-06

GO:0005847

mRNA cleavage and polyadenylation specificity factor complex

2 of 13

1.98

0.89

0.0206

GO:0005736

RNA polymerase I complex

2 of 13

1.98

0.89

0.0206

GO:0005666

RNA polymerase III complex

2 of 16

1.89

0.84

0.0245

GO:0140513

Nuclear protein-containing complex

6 of 537

0.84

0.58

0.0088

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1686

RNA polymerase II, core complex

4 of 12

2.31

2.65

7.49e-06

CL:1974

mRNA cleavage and polyadenylation specificity factor complex

2 of 10

2.09

0.86

0.0251

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

4 of 38

1.81

1.95

5.61e-05

map03015

mRNA surveillance pathway

3 of 81

1.36

0.77

0.0196

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-77075

RNA Pol II CTD phosphorylation and interaction with CE

4 of 27

1.96

1.95

0.00010

MAP-72086

mRNA Capping

4 of 29

1.93

1.94

0.00010

MAP-113418

Formation of the Early Elongation Complex

4 of 29

1.93

1.94

0.00010

MAP-9018519

Estrogen-dependent gene expression

4 of 31

1.9

1.92

0.00010

MAP-75955

RNA Polymerase II Transcription Elongation

4 of 36

1.84

1.87

0.00010

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

4 of 73

1.53

1.08

0.0042

GOCC:0005736

RNA polymerase I complex

2 of 7

2.25

0.93

0.0190

GOCC:0005665

RNA polymerase II, core complex

2 of 8

2.19

0.93

0.0190

GOCC:0005847

mRNA cleavage and polyadenylation specificity factor complex

2 of 11

2.05

0.87

0.0234

GOCC:0055029

Nuclear DNA-directed RNA polymerase complex

3 of 55

1.53

0.82

0.0190

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0240

DNA-directed RNA polymerase

3 of 15

2.09

1.69

0.00052

KW-0349

Heme

2 of 23

1.73

0.68

0.0483

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036866

Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

3 of 12

2.19

1.34

0.0030

IPR022712

Beta-Casp domain

2 of 2

2.79

1.0

0.0153

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01027

Beta-Casp domain

2 of 2

2.79

1.33

0.0038

SM01117

Cytochrome b5-like Heme/Steroid binding domain

2 of 16

1.89

0.7

0.0473

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (18%) [HD]

Permalink

Network

Neighborhood

Textmining

Fusion

Experiments

Cooccurrence

Databases

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About