STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pstBPhosphate import ATP-binding protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (254 aa)    
Predicted Functional Partners:
CDM69096.1
ABC transporters belong to the ATP-Binding Cassette (ABC) superfamily which uses the hydrolysis of ATP to energize diverse biological import and export systems. ABC transporters are minimally constituted of two conserved regions: a highly conserved ATP binding cassette (ABC) and a less conserved transmembrane domain (TMD). These regions can be found on the same protein (mostly in eukaryotes and bacterial exporters) or on two different ones (mostly bacterial importers); High confidence in function and specificity.
 
 
 0.999
CDM69097.1
Phosphate ABC transporter, inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 
 0.999
CDM69098.1
Phosphate-binding periplasmic protein; High confidence in function and specificity.
 
 
 0.999
phoU
Phosphate-specific transport system accessory protein PhoU homolog; Plays a role in the regulation of phosphate uptake.
 
  
 0.997
CDM69869.1
ABC transporter transmembrane domain is main transmembrane structural unit of ATP-binding cassette transporter which consist of six transmembrane domaines. Many members of the ABC transporter family (Pfam PF00005) have two such regions; High confidence in function and specificity.
 
     
0.897
CDM67421.1
ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria; High confidence in function and specificity.
 
     
0.835
CDM69833.1
Hypothetical protein; Family membership.
 
     
0.812
CDM69099.1
Sensor histidine kinase; The HAMP linker domain (present in Histidine kinases, Adenyl cyclases, Methyl-accepting proteins and Phosphatases) is an approximately 50-amino acid alpha-helical region. It is found in bacterial sensor and chemotaxis proteins and in eukaryotic histidine kinases. The bacterial proteins are usually integral membrane proteins and part of a two-component signal transduction pathway; High confidence in function and specificity.
 
   
 0.769
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
   
 0.633
phoP
Transcriptional regulatory protein; Two-component signal transduction systems enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions; High confidence in function and specificity.
  
  
 0.620
Your Current Organism:
Clostridium bornimense
NCBI taxonomy Id: 1216932
Other names: C. bornimense, CECT 8097, Clostridium bornimense Hahnke et al. 2014, Clostridium sp. M2/40, DSM 25664, strain M2/40
Server load: low (18%) [HD]