node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALV29384.1 | ALV29388.1 | APZ00_22000 | APZ00_22020 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.503 |
ALV29384.1 | ALV29389.1 | APZ00_22000 | APZ00_22025 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.487 |
ALV29384.1 | hppA | APZ00_22000 | APZ00_21995 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.484 |
ALV29384.1 | nrdR | APZ00_22000 | APZ00_22030 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.471 |
ALV29384.1 | nusB | APZ00_22000 | APZ00_22010 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.609 |
ALV29384.1 | ribH | APZ00_22000 | APZ00_22015 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.654 |
ALV29384.1 | thiL | APZ00_22000 | APZ00_22005 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.595 |
ALV29388.1 | ALV29384.1 | APZ00_22020 | APZ00_22000 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.503 |
ALV29388.1 | ALV29389.1 | APZ00_22020 | APZ00_22025 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
ALV29388.1 | nrdR | APZ00_22020 | APZ00_22030 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.825 |
ALV29388.1 | nusB | APZ00_22020 | APZ00_22010 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.716 |
ALV29388.1 | ribH | APZ00_22020 | APZ00_22015 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
ALV29388.1 | thiL | APZ00_22020 | APZ00_22005 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.653 |
ALV29389.1 | ALV29384.1 | APZ00_22025 | APZ00_22000 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.487 |
ALV29389.1 | ALV29388.1 | APZ00_22025 | APZ00_22020 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
ALV29389.1 | hppA | APZ00_22025 | APZ00_21995 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. | 0.516 |
ALV29389.1 | nrdR | APZ00_22025 | APZ00_22030 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.944 |
ALV29389.1 | nusB | APZ00_22025 | APZ00_22010 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.853 |
ALV29389.1 | ribH | APZ00_22025 | APZ00_22015 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.995 |
ALV29389.1 | thiL | APZ00_22025 | APZ00_22005 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.885 |