STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mukBUnannotated protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1482 aa)    
Predicted Functional Partners:
mukE
Unannotated protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
 
 
 0.996
mukF
Unannotated protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
 
 
 
 0.996
parC_2
Unannotated protein.
   
 
 0.928
matP
Unannotated protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
 
 
 0.918
smtA
Unannotated protein; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
  
  
 0.818
acpP
Unannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
   0.789
pgpB_2
Unannotated protein.
  
     0.752
GCA_001598715_02073
Unannotated protein.
  
     0.742
nadR
Unannotated protein.
  
     0.714
uspA_1
Unannotated protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
  
     0.689
Your Current Organism:
Klebsiella pneumoniae ozaenae
NCBI taxonomy Id: 1218098
Other names: K. pneumoniae subsp. ozaenae NBRC 105683, Klebsiella pneumoniae subsp. ozaenae NBRC 105683
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.