node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LY56_01906 | LY56_02318 | GCA_001870675_00934 | GCA_001870675_03282 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein. | 0.449 |
LY56_01906 | LY56_03193 | GCA_001870675_00934 | GCA_001870675_00751 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein; Belongs to the ClpA/ClpB family. | 0.800 |
LY56_01906 | dnaJ | GCA_001870675_00934 | GCA_001870675_00531 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.569 |
LY56_01906 | dnaK | GCA_001870675_00934 | GCA_001870675_00532 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.686 |
LY56_01906 | grpE | GCA_001870675_00934 | GCA_001870675_00194 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.617 |
LY56_01906 | hslU | GCA_001870675_00934 | GCA_001870675_01631 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.541 |
LY56_02286 | LY56_02318 | GCA_001870675_03250 | GCA_001870675_03282 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein. | 0.557 |
LY56_02286 | LY56_03193 | GCA_001870675_03250 | GCA_001870675_00751 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein; Belongs to the ClpA/ClpB family. | 0.793 |
LY56_02286 | dnaJ | GCA_001870675_03250 | GCA_001870675_00531 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.449 |
LY56_02286 | dnaK | GCA_001870675_03250 | GCA_001870675_00532 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.624 |
LY56_02286 | grpE | GCA_001870675_03250 | GCA_001870675_00194 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.544 |
LY56_02286 | hslU | GCA_001870675_03250 | GCA_001870675_01631 | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | Unannotated protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.488 |
LY56_02318 | LY56_01906 | GCA_001870675_03282 | GCA_001870675_00934 | Unannotated protein. | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | 0.449 |
LY56_02318 | LY56_02286 | GCA_001870675_03282 | GCA_001870675_03250 | Unannotated protein. | Unannotated protein; Belongs to the small heat shock protein (HSP20) family. | 0.557 |
LY56_02318 | LY56_02676 | GCA_001870675_03282 | GCA_001870675_00695 | Unannotated protein. | Unannotated protein. | 0.435 |
LY56_02318 | LY56_03193 | GCA_001870675_03282 | GCA_001870675_00751 | Unannotated protein. | Unannotated protein; Belongs to the ClpA/ClpB family. | 0.756 |
LY56_02318 | clpP | GCA_001870675_03282 | GCA_001870675_02865 | Unannotated protein. | Unannotated protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.435 |
LY56_02318 | dnaK | GCA_001870675_03282 | GCA_001870675_00532 | Unannotated protein. | Unannotated protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.998 |
LY56_02318 | grpE | GCA_001870675_03282 | GCA_001870675_00194 | Unannotated protein. | Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...] | 0.918 |
LY56_02318 | hslU | GCA_001870675_03282 | GCA_001870675_01631 | Unannotated protein. | Unannotated protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.689 |