STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaBUnannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (482 aa)    
Predicted Functional Partners:
guaA
Unannotated protein; Catalyzes the synthesis of GMP from XMP.
 0.999
purA
Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
 0.993
LY56_02484
Unannotated protein.
  
 
 0.975
LY56_00422
Unannotated protein.
 
 
 0.974
purH
Unannotated protein.
  
 
 0.965
LY56_01634
Unannotated protein; Belongs to the SIS family. GutQ/KpsF subfamily.
  
 
 0.953
LY56_01083
Unannotated protein.
    
 0.940
LY56_00128
Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.939
LY56_00861
Unannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.932
LY56_00553
Unannotated protein.
  
 
 0.931
Your Current Organism:
Roseinatronobacter thiooxidans
NCBI taxonomy Id: 121821
Other names: DSM 13087, R. thiooxidans, Roseinatronobacter thiooxidans Sorokin et al. 2000, strain ALG 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.