STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiD-2Phosphomethylpyrimidine kinase. (267 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
JF75_18270
Putative thiaminase; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.
 
 0.998
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
 
 0.997
clpE
ATP-dependent Clp protease, ATP-binding subunit; Belongs to the ClpA/ClpB family.
  
 
 0.750
clpC
ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.750
JF75_18980
ATP-dependent protease; Belongs to the ClpA/ClpB family.
  
 
 0.750
JF75_05150
Aryl-alcohol dehydrogenase related enzyme.
  
 
 0.748
JF75_11730
Thiamine pyrophosphokinase.
    
 0.744
nudF
ADP-ribose pyrophosphatase.
  
 
 0.729
JF75_09630
Serine/threonine protein phosphatase family protein.
    
  0.688
Your Current Organism:
Lactobacillus kimbladii
NCBI taxonomy Id: 1218506
Other names: CCUG 63633, DSM 26263, L. kimbladii, Lactobacillus kimbladii Olofsson et al. 2014, Lactobacillus sp. H6HS28N, Lactobacillus sp. Hma2N, strain Hma2N
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