STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EMY71514.1N-6 DNA Methylase. (516 aa)    
Predicted Functional Partners:
EMY71558.1
Type I restriction modification DNA specificity domain protein.
 
 
 0.999
EMY71521.1
PF11867 domain protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 
 0.997
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
   
 
 0.761
EMY68068.1
Toxin-antitoxin system, toxin component, Fic family.
  
    0.745
EMY69866.1
AAA domain protein.
  
  
 0.673
EMY67777.1
AAA domain protein.
  
  
 0.670
EMY71538.1
Hypothetical protein.
       0.550
EMY71547.1
PF04343 family protein.
       0.543
EMY70335.1
Sugar isomerase, KpsF/GutQ family; Belongs to the SIS family. GutQ/KpsF subfamily.
   
 
 0.484
guaA
GMP synthase (glutamine-hydrolyzing).
     
 0.418
Your Current Organism:
Leptospira vanthielii
NCBI taxonomy Id: 1218591
Other names: L. vanthielii serovar Holland str. Waz Holland = ATCC 700522, Leptospira genomosp. 3 str. ATCC 700522, Leptospira vanthielii serovar Holland str. ATCC 700522 = Waz Holland, Leptospira vanthielii serovar Holland str. Waz Holland, Leptospira vanthielii serovar Holland str. Waz Holland = ATCC 700522
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