STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ndkNucleoside pyrophosphate kinase. (131 aa)    
Predicted Functional Partners:
rpsB
Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
   
 0.997
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
  0.997
EMY69537.1
Ribosomal protein S10p/S20e-like protein.
   
  0.997
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
  0.997
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
 0.997
rpsP
Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
 0.996
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
 0.995
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
  0.995
rpsI
Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
  0.994
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
  
  0.993
Your Current Organism:
Leptospira vanthielii
NCBI taxonomy Id: 1218591
Other names: L. vanthielii serovar Holland str. Waz Holland = ATCC 700522, Leptospira genomosp. 3 str. ATCC 700522, Leptospira vanthielii serovar Holland str. ATCC 700522 = Waz Holland, Leptospira vanthielii serovar Holland str. Waz Holland, Leptospira vanthielii serovar Holland str. Waz Holland = ATCC 700522
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