STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icdIsocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (410 aa)    
Predicted Functional Partners:
sucA
2-oxoglutarate dehydrogenase E1 component.
   
 
 0.987
acnA
Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.974
acnA-2
Aconitase.
  
 0.974
mdh-2
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.967
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.958
GAO42888.1
Putative 2-oxoglutarate--ferredoxin oxidoreductase alpha subunit.
   
 
 0.953
icd-2
Isocitrate dehydrogenase.
  
 0.952
katE
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 0.942
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
  
 0.941
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.935
Your Current Organism:
Flavihumibacter petaseus
NCBI taxonomy Id: 1220578
Other names: F. petaseus NBRC 106054, Flavihumibacter petaseus NBRC 106054, Flavihumibacter petaseus T41, Sphingobacteriales bacterium T41
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