STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W2RXG9_9EUROAP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (754 aa)    
Predicted Functional Partners:
W2SA65_9EURO
AP-1 complex subunit gamma.
   
0.954
W2S682_9EURO
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
  
 
 0.953
W2RW58_9EURO
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
   
 0.951
W2S737_9EURO
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
 0.944
W2RRI2_9EURO
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.943
W2RZD0_9EURO
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.941
W2SE58_9EURO
ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family.
    
 0.921
W2RRD1_9EURO
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.913
W2RTD3_9EURO
AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.
   
 0.898
W2RUN2_9EURO
Zn(2)-C6 fungal-type domain-containing protein.
    
 0.883
Your Current Organism:
Cyphellophora europaea
NCBI taxonomy Id: 1220924
Other names: C. europaea CBS 101466, Cyphellophora europaea CBS 101466, Phialophora europaea CBS 101466
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.