STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W2RYY8_9EUROU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (197 aa)    
Predicted Functional Partners:
W2RZ28_9EURO
Small nuclear ribonucleoprotein Sm D2.
   
 0.997
W2S165_9EURO
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.996
W2S8E6_9EURO
RRM domain-containing protein.
   
 0.996
W2S3V5_9EURO
Small nuclear ribonucleoprotein G.
   
 0.995
W2RYF6_9EURO
Sm domain-containing protein.
   
 0.993
W2RRW7_9EURO
Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family.
   
 0.992
W2RRF9_9EURO
Sm domain-containing protein.
   
 0.991
W2S2P1_9EURO
Uncharacterized protein.
   
 
 0.990
W2SBD0_9EURO
PWI domain-containing protein.
   
 
 0.990
W2S3D9_9EURO
SF3b1 domain-containing protein.
   
 0.984
Your Current Organism:
Cyphellophora europaea
NCBI taxonomy Id: 1220924
Other names: C. europaea CBS 101466, Cyphellophora europaea CBS 101466, Phialophora europaea CBS 101466
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