STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W2S3E9_9EURODUF2236 domain-containing protein. (482 aa)    
Predicted Functional Partners:
W2RU87_9EURO
Uncharacterized protein.
    
 0.953
W2RNM0_9EURO
BAH domain-containing protein.
    
 
 0.929
W2RT36_9EURO
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.912
W2RY45_9EURO
Uncharacterized protein.
    
 0.896
W2S7M7_9EURO
Histone H2A; Belongs to the histone H2A family.
   
 0.880
W2SA11_9EURO
Histone H2A; Belongs to the histone H2A family.
   
 0.877
W2SEF0_9EURO
Uncharacterized protein.
   
 
 0.870
W2S777_9EURO
WD_REPEATS_REGION domain-containing protein.
   
 0.861
W2RK36_9EURO
Uncharacterized protein.
    
 0.844
W2S190_9EURO
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
   
 0.837
Your Current Organism:
Cyphellophora europaea
NCBI taxonomy Id: 1220924
Other names: C. europaea CBS 101466, Cyphellophora europaea CBS 101466, Phialophora europaea CBS 101466
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.