QY95_01092 protein (Quasibacillus thermotolerans)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

QY95_01092

DUF2529 domain-containing protein. (174 aa)

Predicted Functional Partners:

QY95_01424

0.767

QY95_00077

0.756

QY95_02756

0.749

QY95_01538

0.734

ftsL

0.703

QY95_00071

0.701

QY95_02697

0.698

QY95_01712

0.676

QY95_00004

0.660

QY95_00467

0.655

Your Current Organism:

Quasibacillus thermotolerans

NCBI taxonomy Id: 1221996
Other names: Bacillaceae bacterium 5.5LF48TDT, Bacillaceae bacterium MTCC 8252, Bacillus sp. SgZ-8, Bacillus thermotolerans, Bacillus thermotolerans Yang et al. 2013, CCTCC AB 2012108, KACC 16706, Q. thermotolerans, strain SgZ-8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
QY95_00004	QY95_01092	QY95_00004	QY95_01092	Dipeptidyl aminopeptidase.	DUF2529 domain-containing protein.	0.660
QY95_00004	QY95_01424	QY95_00004	QY95_01424	Dipeptidyl aminopeptidase.	Protease production regulatory protein Hpr (ScoC).	0.440
QY95_00071	QY95_00077	QY95_00071	QY95_00077	Uncharacterized protein.	Uncharacterized protein.	0.760
QY95_00071	QY95_00467	QY95_00071	QY95_00467	Uncharacterized protein.	NADH dehydrogenase.	0.418
QY95_00071	QY95_01092	QY95_00071	QY95_01092	Uncharacterized protein.	DUF2529 domain-containing protein.	0.701
QY95_00071	QY95_01424	QY95_00071	QY95_01424	Uncharacterized protein.	Protease production regulatory protein Hpr (ScoC).	0.615
QY95_00071	QY95_01538	QY95_00071	QY95_01538	Uncharacterized protein.	Putative Membrane Spanning Protein.	0.774
QY95_00071	QY95_01712	QY95_00071	QY95_01712	Uncharacterized protein.	Transcription regulator.	0.708
QY95_00071	QY95_02756	QY95_00071	QY95_02756	Uncharacterized protein.	Uncharacterized protein.	0.781
QY95_00077	QY95_00071	QY95_00077	QY95_00071	Uncharacterized protein.	Uncharacterized protein.	0.760
QY95_00077	QY95_00467	QY95_00077	QY95_00467	Uncharacterized protein.	NADH dehydrogenase.	0.787
QY95_00077	QY95_01092	QY95_00077	QY95_01092	Uncharacterized protein.	DUF2529 domain-containing protein.	0.756
QY95_00077	QY95_01424	QY95_00077	QY95_01424	Uncharacterized protein.	Protease production regulatory protein Hpr (ScoC).	0.780
QY95_00077	QY95_01538	QY95_00077	QY95_01538	Uncharacterized protein.	Putative Membrane Spanning Protein.	0.768
QY95_00077	QY95_01712	QY95_00077	QY95_01712	Uncharacterized protein.	Transcription regulator.	0.773
QY95_00077	QY95_02697	QY95_00077	QY95_02697	Uncharacterized protein.	Uncharacterized protein.	0.614
QY95_00077	QY95_02756	QY95_00077	QY95_02756	Uncharacterized protein.	Uncharacterized protein.	0.770
QY95_00077	ftsL	QY95_00077	QY95_00114	Uncharacterized protein.	Cell division protein FtsL; Essential cell division protein; Belongs to the FtsL family.	0.448
QY95_00467	QY95_00071	QY95_00467	QY95_00071	NADH dehydrogenase.	Uncharacterized protein.	0.418
QY95_00467	QY95_00077	QY95_00467	QY95_00077	NADH dehydrogenase.	Uncharacterized protein.	0.787

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.954

expected number of edges:

40

PPI enrichment p-value:

0.921

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016310

Phosphorylation

7 of 160

1.22

1.28

6.14e-05

GO:0007165

Signal transduction

7 of 188

1.15

1.16

9.03e-05

GO:0050794

Regulation of cellular process

8 of 502

0.78

0.63

0.0012

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004672

Protein kinase activity

7 of 92

1.46

2.0

8.47e-07

GO:0000155

Phosphorelay sensor kinase activity

6 of 68

1.52

1.98

3.63e-06

GO:0008556

P-type potassium transmembrane transporter activity

2 of 3

2.4

1.27

0.0046

GO:0016772

Transferase activity, transferring phosphorus-containing groups

8 of 245

1.09

1.24

3.63e-06

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

7 of 563

0.67

0.47

0.0087

GO:0016021

Integral component of membrane

9 of 913

0.57

0.42

0.0066

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3493

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain, and EAL domain

6 of 21

2.03

3.56

1.22e-08

CL:3496

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain, and cheY-homologous receiver domain

5 of 13

2.16

3.49

5.10e-08

CL:3481

Phosphorelay sensor kinase activity, and Domain present in phytochromes and cGMP-specific phosphodiesterases.

7 of 47

1.75

3.02

1.22e-08

CL:3939

P-type ion transporter activity, and UspA

2 of 5

2.18

1.06

0.0103

CL:3500

Mixed, incl. PAC motif, and Sodium/solute symporter

2 of 6

2.1

1.01

0.0126

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031004

Potassium ion-transporting ATPase complex

2 of 3

2.4

0.93

0.0194

GOCC:0016020

Membrane

8 of 786

0.58

0.39

0.0194

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

6 of 95

1.38

1.61

1.75e-05

KW-0633

Potassium transport

2 of 4

2.28

1.05

0.0113

KW-0418

Kinase

4 of 108

1.15

0.75

0.0113

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

6 of 42

1.73

2.51

6.46e-07

IPR036097

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily

6 of 47

1.68

2.41

8.02e-07

IPR036890

Histidine kinase/HSP90-like ATPase superfamily

7 of 67

1.6

2.39

2.25e-07

IPR005467

Histidine kinase domain

6 of 50

1.66

2.35

8.48e-07

IPR013656

PAS fold-4

4 of 15

2.0

2.18

3.39e-05

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00388

His Kinase A (phosphoacceptor) domain

6 of 45

1.7

2.63

1.61e-07

SM00387

Histidine kinase-like ATPases

6 of 60

1.58

2.3

4.01e-07

SM00091

PAS domain

4 of 30

1.7

1.85

5.75e-05

SM00086

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

3 of 16

1.85

1.65

0.00038

SM00448

cheY-homologous receiver domain

5 of 81

1.37

1.48

5.75e-05

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