STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
QY95_01939Uncharacterized protein. (482 aa)    
Predicted Functional Partners:
cinA
Putative competence-damage inducible protein; Belongs to the CinA family.
   
 
  0.725
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
   
 
  0.720
QY95_01167
Phosphodiesterase/alkaline phosphatase D.
 
  
 0.703
tatA-3
Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
       0.666
QY95_01834
Aminopeptidase Y (Arg, Lys, Leu preference).
  
     0.626
QY95_03099
Glycerophosphoryl diester phosphodiesterase.
  
 
  0.601
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.560
QY95_01625
dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.557
QY95_01876
Putative secreted protein.
  
 
  0.545
QY95_01260
Uncharacterized protein.
     
 0.535
Your Current Organism:
Quasibacillus thermotolerans
NCBI taxonomy Id: 1221996
Other names: Bacillaceae bacterium 5.5LF48TDT, Bacillaceae bacterium MTCC 8252, Bacillus sp. SgZ-8, Bacillus thermotolerans, Bacillus thermotolerans Yang et al. 2013, CCTCC AB 2012108, KACC 16706, Q. thermotolerans, strain SgZ-8
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