STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHI22611.1Hypothetical protein. (605 aa)    
Predicted Functional Partners:
AHI22612.1
Hypothetical protein.
 
     0.792
AHI22610.1
Hypothetical protein; COG1230 Co/Zn/Cd efflux system component.
       0.783
AHI22613.1
COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.594
AHI23059.1
Hypothetical protein.
  
     0.576
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.566
AHI21651.1
COG4861 Uncharacterized protein conserved in bacteria.
  
     0.555
ilvH
COG0440 Acetolactate synthase, small (regulatory) subunit.
       0.512
AHI22607.1
Acetolactate synthase 1 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].
       0.506
AHI23678.1
Hypothetical protein.
  
     0.495
AHI22646.1
Hypothetical protein.
  
     0.488
Your Current Organism:
Corynebacterium vitaeruminis
NCBI taxonomy Id: 1224164
Other names: C. vitaeruminis DSM 20294, Corynebacterium vitaeruminis ATCC 10234, Corynebacterium vitaeruminis CIP 82.7, Corynebacterium vitaeruminis DSM 20294
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.