STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
siaCPolysialic acid capsule biosynthesis protein SiaC; Identified by similarity to EGAD:19609; match to protein family HMM PF01354; match to protein family HMM PF03102. (349 aa)    
Predicted Functional Partners:
siaB
Polysialic acid capsule biosynthesis protein SiaB; Identified by similarity to EGAD:14454; match to protein family HMM PF02348; Belongs to the CMP-NeuNAc synthase family.
 
 0.999
synX
Polysialic acid capsule biosynthesis protein SynX; Catalyzes the conversion of UDP-N-acetylglucosamine (UDP- GlcNAc) to UDP and N-acetyl-D-mannosamine (ManNAc).
 
 
 0.999
NMB0353
Conserved hypothetical protein; Identified by similarity to EGAD:155354; match to protein family HMM TIGR01662; match to protein family HMM TIGR01670.
  
 0.925
ctrD
Capsule polysaccharide export ATP-binding protein CtrD; Putative ATP-binding protein, and an energy-coupling component of capsule polysaccharide export apparatus.
  
  
 0.804
ctrA
Capsule polysaccharide export outer membrane protein CtrA; Involved in transport of capsular polysaccharides to the cell surface. May function as a membrane anchor for capsular polysaccharides. Possible porin properties; Belongs to the BexD/CtrA/VexA family.
  
  
 0.799
ctrC
Capsule polysaccharide export inner-membrane protein CtrC; May form an ATP-driven capsule polysaccharide export apparatus, in association with the CtrB and CtrD proteins; Belongs to the ABC-2 integral membrane protein family.
     
 0.642
pglB
Pilin glycosylation protein PglB; Identified by similarity to GB:3299889; match to protein family HMM PF00132; match to protein family HMM PF02397.
  
  
 0.603
ctrB
Capsule polysaccharide export inner-membrane protein CtrB; May form an ATP-driven capsule polysaccharide export apparatus, in association with the CtrC and CtrD proteins; Belongs to the BexC/CtrB/KpsE family.
     
 0.598
NMB0067
Polysialic acid capsule biosynthesis protein SiaD, truncation; Identified by similarity to GP:530041.
       0.551
pglC
Pilin glycosylation protein PglC; Identified by similarity to GP:3299890; match to protein family HMM PF01041; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.532
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.