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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipACapsule polysaccharide modification protein LipA; Involved in the phospholipid modification of the capsular polysaccharide, a strong requirement for its translocation to the cell surface. (704 aa)    
Predicted Functional Partners:
lipB
Capsule polysaccharide modification protein LipB; Involved in the phospholipid modification of the capsular polysaccharide, a strong requirement for its translocation to the cell surface.
  
 0.968
ctrC
Capsule polysaccharide export inner-membrane protein CtrC; May form an ATP-driven capsule polysaccharide export apparatus, in association with the CtrB and CtrD proteins; Belongs to the ABC-2 integral membrane protein family.
 
  
 0.953
ctrB
Capsule polysaccharide export inner-membrane protein CtrB; May form an ATP-driven capsule polysaccharide export apparatus, in association with the CtrC and CtrD proteins; Belongs to the BexC/CtrB/KpsE family.
 
  
 0.952
ctrD
Capsule polysaccharide export ATP-binding protein CtrD; Putative ATP-binding protein, and an energy-coupling component of capsule polysaccharide export apparatus.
 
  
 0.951
ctrA
Capsule polysaccharide export outer membrane protein CtrA; Involved in transport of capsular polysaccharides to the cell surface. May function as a membrane anchor for capsular polysaccharides. Possible porin properties; Belongs to the BexD/CtrA/VexA family.
 
  
 0.944
NMB0081
dTDP-4-keto-6-deoxy-D-glucose-3,6-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
    0.718
NMB0352
Sugar isomerase, KpsF/GutQ family; Identified by similarity to EGAD:29719; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily.
     
 0.658
rfbA-2
Glucose-1-phosphate thymidylyltransferase; Identified by similarity to EGAD:23719; match to protein family HMM PF00483; match to protein family HMM TIGR01207.
       0.586
rfbB-2
dTDP-D-glucose 4,6-dehydratase; Identified by similarity to EGAD:40672; match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM TIGR01181.
       0.456
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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