Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NMB0088Putative outer membrane protein P1; Identified by similarity to EGAD:16317; match to protein family HMM PF03349; Belongs to the OmpP1/FadL family. (466 aa)    
Predicted Functional Partners:
omp85
Outer membrane protein Omp85; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane; Belongs to the BamA family.
  
 
 
 0.865
comL
Competence lipoprotein ComL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Required for efficient transformation of Neisseria meningitidis by species-related DNA; Belongs to the BamD family.
    
 
 0.862
NMB1796
Conserved hypothetical protein; Identified by similarity to EGAD:20585; match to protein family HMM PF03358.
      
 0.774
NMB0928
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.773
NMB1612
Amino acid ABC transporter, periplasmic amino acid-binding protein; Identified by similarity to EGAD:8642; match to protein family HMM PF00497; Belongs to the bacterial solute-binding protein 3 family.
   
  
 0.772
fbp-2
FKBP-type peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins.
    
 
 0.708
fkpA
Macrophage infectivity potentiator; Identified by similarity to GP:2231726; match to protein family HMM PF00254; match to protein family HMM PF01346.
    
 
 0.708
nspA
Outer membrane protein NspA; Identified by similarity to EGAD:137514; match to protein family HMM PF02462.
  
  
 0.571
pykA
Pyruvate kinase II; Identified by similarity to EGAD:21471; match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
     
 0.521
NMB0947
Putative 2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to EGAD:23102; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992.
   
 
  0.513
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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