Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NMB0271Hypothetical protein; Identified by Glimmer2; putative. (262 aa)    
Predicted Functional Partners:
fabF-1
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
     
 0.900
bioC
Putative biotin synthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
     
  0.900
fabF-2
3-oxoacyl-(acyl-carrier-protein) synthase II; Identified by similarity to EGAD:125117; match to protein family HMM PF00109; match to protein family HMM PF02801; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
 0.900
bioH
Putative bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
 
  
 0.814
NMB0409
Conserved hypothetical protein; Identified by similarity to EGAD:48967; match to protein family HMM PF02636.
  
     0.667
NMB0314
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.645
NMB0269
Competence protein; Identified by similarity to EGAD:18112.
       0.591
NMB0928
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.540
NMB0266
Conserved hypothetical protein; Identified by similarity to EGAD:107494; match to protein family HMM PF03413.
 
 
   0.525
NMB1045
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.495
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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