Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ispZIntracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (176 aa)    
Predicted Functional Partners:
NMB0344
BolA/YrbA family protein; Identified by similarity to EGAD:21163; match to protein family HMM PF01722; Belongs to the BolA/IbaG family.
  
    0.794
NMB0343
Conserved hypothetical protein; Identified by similarity to GP:902447; match to protein family HMM PF03795.
  
    0.788
NMB0444
Conserved hypothetical protein; Identified by similarity to EGAD:107888; match to protein family HMM PF00892.
   
  
 0.776
NMB0866
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.772
dusA
Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
     
 0.647
NMB0345
Putative cell-binding factor; Identified by similarity to EGAD:12394.
       0.596
NMB0346
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.524
NMB1882
TonB-dependent receptor; Identified by similarity to EGAD:8251; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783.
      
 0.524
thrB
Homoserine kinase; Identified by similarity to GP:3089616; match to protein family HMM PF01636; match to protein family HMM TIGR00938; Belongs to the pseudomonas-type ThrB family.
  
     0.499
NMB0341
tspA protein; Identified by similarity to GP:3413497; match to protein family HMM PF01476.
       0.490
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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