STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rmpMOuter membrane protein class 4; Identified by similarity to EGAD:10394; match to protein family HMM PF00691. (242 aa)    
Predicted Functional Partners:
porA
Outer membrane protein PorA; Serves as a slightly cation selective porin. Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity.
  
 0.961
omp85
Outer membrane protein Omp85; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane; Belongs to the BamA family.
  
 
 0.958
porB
Major outer membrane protein PIB; Serves as a slightly cation selective porin; Belongs to the Gram-negative porin family.
  
 0.954
comL
Competence lipoprotein ComL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Required for efficient transformation of Neisseria meningitidis by species-related DNA; Belongs to the BamD family.
  
  
 0.861
bamE
Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
  
 0.799
exbB
Biopolymer transport protein ExbB; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
 
   
 0.766
NMB0383
Hypothetical protein; Identified by Glimmer2; putative.
       0.709
exbD
Biopolymer transport protein ExbD; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
 
 
 0.683
pilB
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
  
 
 0.665
NMB0181
Putative outer membrane protein OmpH; Identified by similarity to EGAD:24192; match to protein family HMM PF03938; Belongs to the skp family.
 
 
 0.663
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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