Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pgmBBeta-phosphoglucomutase; Identified by similarity to EGAD:125152; match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01990; match to protein family HMM TIGR02009. (221 aa)    
Predicted Functional Partners:
mapA
Maltose phosphorylase; Identified by similarity to GP:3724125; match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636.
 
 0.999
galU
UTP--glucose-1-phosphate uridylyltransferase; Identified by similarity to EGAD:153516; match to protein family HMM PF00483; match to protein family HMM TIGR01099.
      
 0.795
galM
Aldose 1-epimerase; Identified by similarity to EGAD:7305; match to protein family HMM PF01263.
 
  
 0.633
NMB0388
Putative sugar transporter; Identified by similarity to EGAD:62114; match to protein family HMM PF07690.
 
    0.626
galE
UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Plays an essential role in the incorporation of galactose into meningococcal lipopolysaccharide surface molecules, which are important for pathogenesis. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD.
     
 0.513
rfaD
ADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
   
  
 0.444
gmhB
Putative histidinol-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position. Belongs to the GmhB family.
   
  
 0.439
rfaF
ADP-heptose--LPS heptosyltransferase II; Identified by similarity to EGAD:40767; match to protein family HMM PF01075; match to protein family HMM TIGR02195.
   
  
 0.434
pilB
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
     
 0.400
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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