STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (370 aa)    
Predicted Functional Partners:
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
 0.999
nadC
Nicotinate-nucleotide pyrophosphorylase; Identified by similarity to EGAD:42463; match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD family.
 
 
 0.999
porA
Outer membrane protein PorA; Serves as a slightly cation selective porin. Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity.
   
  
 0.823
opc
Class 5 outer membrane protein; Identified by similarity to GP:1177565; match to protein family HMM PF07239.
      
 0.821
porB
Major outer membrane protein PIB; Serves as a slightly cation selective porin; Belongs to the Gram-negative porin family.
   
  
 0.820
NMB0395
Conserved hypothetical protein; Identified by similarity to EGAD:161074.
 
    0.780
hsf
Adhesin; Involved in adhesion of capsulated meningococci to host epithelial cells. Interacts with laminin and heparan sulfate, promoting the adherence to the extracellular matrix (ECM) components.
      
 0.754
pilQ
pilQ protein; Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA (By similarity); Belongs to the bacterial secretin family. PilQ subfamily.
      
 0.747
cysE
Serine acetyltransferase; Identified by similarity to EGAD:29240; match to protein family HMM PF00132; match to protein family HMM PF06426; match to protein family HMM TIGR01172.
  
    0.737
NMB1870
Hypothetical protein; Identified by Glimmer2; putative.
   
  
 0.714
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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