Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ftsLCell division protein FtsL-related protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (89 aa)    
Predicted Functional Partners:
NMB0356
ABC transporter, ATP-binding protein; Identified by similarity to EGAD:139998; match to protein family HMM PF00005.
  
 
 0.891
lptA
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
  
 
 0.817
mraZ
Conserved hypothetical protein; Identified by similarity to EGAD:6617; match to protein family HMM PF02381; match to protein family HMM TIGR00242; Belongs to the MraZ family.
  
    0.775
rsmH
Conserved hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
       0.773
NMB1570
Conserved hypothetical protein; Identified by similarity to EGAD:24062; match to protein family HMM PF03739.
  
 
 0.681
NMB1571
Conserved hypothetical protein; Identified by similarity to EGAD:28691; match to protein family HMM PF03739.
  
 
 0.681
penA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
  
    0.595
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
    0.545
NMB0352
Sugar isomerase, KpsF/GutQ family; Identified by similarity to EGAD:29719; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily.
  
  
 0.492
NMB0409
Conserved hypothetical protein; Identified by similarity to EGAD:48967; match to protein family HMM PF02636.
       0.426
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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