Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NMB0441Nitrilase; Identified by similarity to EGAD:47743; match to protein family HMM PF00795. (270 aa)    
Predicted Functional Partners:
cnp1
Cryptic protein; Identified by similarity to EGAD:20133.
   
    0.731
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.583
NMB0440
Putative prephenate dehydrogenase; Identified by similarity to EGAD:156224; match to protein family HMM PF02153.
  
    0.566
NMB0541
Hypothetical protein; Identified by Glimmer2; putative.
   
    0.460
pheA
Chorismate mutase/prephenate dehydratase; Identified by similarity to GP:4105530; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01807.
  
  
 0.435
NMB2157
Putative pyrazinamidase/nicotinamidase PncA; Identified by similarity to EGAD:140533; match to protein family HMM PF00857.
  
 
 0.426
nadD
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.412
nadC
Nicotinate-nucleotide pyrophosphorylase; Identified by similarity to EGAD:42463; match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD family.
  
  
 0.410
pilB
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
  
 
 0.404
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
     
 0.404
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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