STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tbp1Transferrin-binding protein 1; Acts as a transferrin receptor and is required for transferrin utilization; Belongs to the TonB-dependent receptor family. (915 aa)    
Predicted Functional Partners:
tbp2
Transferrin-binding protein 2; Acts as a transferrin receptor and is required for transferrin utilization.
  
 
 0.992
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Required for heme utilization and virulence.
 
 
 0.954
mlp
Lipoprotein; Identified by similarity to EGAD:40759; match to protein family HMM PF04355.
  
   
 0.783
NMB0313
Conserved hypothetical protein; Identified by similarity to GP:3523136; match to protein family HMM PF04575; match to protein family HMM PF07719.
  
    0.776
NMB1645
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.750
NMB1210
Putative toxin-activating protein; Identified by similarity to GP:551169; match to protein family HMM PF02794.
  
     0.740
NMB1634
Conserved hypothetical protein; Identified by similarity to GP:3402495; match to protein family HMM PF02486.
  
     0.732
NMB0964
TonB-dependent receptor; Probable receptor, TonB-dependent.
  
  
 0.728
NMB1551
Conserved hypothetical protein; Identified by similarity to GP:3402502; match to protein family HMM PF05707.
  
     0.727
NMB1626
Conserved hypothetical protein; Identified by similarity to GP:3402502; match to protein family HMM PF05707.
  
     0.727
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.