STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbp1Transferrin-binding protein 1; Acts as a transferrin receptor and is required for transferrin utilization; Belongs to the TonB-dependent receptor family. (915 aa)    
Predicted Functional Partners:
tbp2
Transferrin-binding protein 2; Acts as a transferrin receptor and is required for transferrin utilization.
  
 
 0.984
NMB0964
TonB-dependent receptor; Probable receptor, TonB-dependent.
  
  
 0.812
NMB0313
Conserved hypothetical protein; Identified by similarity to GP:3523136; match to protein family HMM PF04575; match to protein family HMM PF07719.
  
    0.778
mlp
Lipoprotein; Identified by similarity to EGAD:40759; match to protein family HMM PF04355.
  
  
 0.774
NMB1645
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.750
NMB1210
Putative toxin-activating protein; Identified by similarity to GP:551169; match to protein family HMM PF02794.
  
    0.741
NMB1634
Conserved hypothetical protein; Identified by similarity to GP:3402495; match to protein family HMM PF02486.
  
     0.732
NMB1551
Conserved hypothetical protein; Identified by similarity to GP:3402502; match to protein family HMM PF05707.
  
     0.727
NMB1626
Conserved hypothetical protein; Identified by similarity to GP:3402502; match to protein family HMM PF05707.
  
     0.727
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Required for heme utilization and virulence.
 
 
 0.723
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.