Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NMB0479Conserved hypothetical protein; Identified by similarity to EGAD:156541; match to protein family HMM PF03259. (119 aa)    
Predicted Functional Partners:
NMB0477
Conserved hypothetical protein; Identified by similarity to EGAD:156531; match to protein family HMM PF03029; match to protein family HMM TIGR00231.
 
 
 0.995
NMB0476
Hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.993
NMB0478
Hypothetical protein; Identified by Glimmer2; putative.
 
    0.948
NMB1528
Putative methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
   
  
 0.776
NMB1529
Hypothetical protein; Identified by Glimmer2; putative.
      
 0.774
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
      
 0.773
NMB0475
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.710
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
      
 0.627
NMB0451
Hypothetical protein; Identified by Glimmer2; putative.
   
    0.572
rfaF
ADP-heptose--LPS heptosyltransferase II; Identified by similarity to EGAD:40767; match to protein family HMM PF01075; match to protein family HMM TIGR02195.
      
 0.510
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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