Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NMB0674Conserved hypothetical protein; Identified by similarity to EGAD:90683; match to protein family HMM PF03966; Belongs to the UPF0434 family. (60 aa)    
Predicted Functional Partners:
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
  
  
 0.860
NMB0676
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.709
NMB0673
Hypothetical protein; Identified by Glimmer2; putative.
       0.576
lpxK
Tetraacyldisaccharide 4`-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
     0.531
NMB1786
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.486
NMB0677
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.473
ispZ
Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
  
     0.466
ispA
Geranyltranstransferase; Identified by similarity to EGAD:28427; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
   
    0.450
prmB
Putative adenine specific methylase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
  
   0.447
tufA
Translation elongation factor Tu; Identified by similarity to EGAD:31897; match to protein family HMM PF00009; match to protein family HMM PF03143; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR00485.
   
    0.426
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.