NMB0734 protein (Neisseria meningitidis) - STRING interaction network

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NMB0734

Hypothetical protein; Identified by Glimmer2; putative. (158 aa)

Predicted Functional Partners:

ubiA

0.993

pheA

0.889

trpE

0.812

aspC

0.800

pabA

0.800

hisC

0.800

tyrB

0.800

aroC

0.800

NMB1565

0.760

bioD

0.752

Your Current Organism:

Neisseria meningitidis

NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NMB0734	NMB1565	NMB0734	NMB1565	Hypothetical protein; Identified by Glimmer2; putative.	Hypothetical protein; Identified by Glimmer2; putative.	0.760
NMB0734	aroC	NMB0734	NMB1680	Hypothetical protein; Identified by Glimmer2; putative.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.800
NMB0734	aspC	NMB0734	NMB0540	Hypothetical protein; Identified by Glimmer2; putative.	Aspartate aminotransferase; Identified by similarity to EGAD:28598; match to protein family HMM PF00155.	0.800
NMB0734	bioD	NMB0734	NMB0733	Hypothetical protein; Identified by Glimmer2; putative.	Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.752
NMB0734	hisC	NMB0734	NMB1582	Hypothetical protein; Identified by Glimmer2; putative.	Histidinol-phosphate aminotransferase; Identified by similarity to EGAD:156515; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.800
NMB0734	pabA	NMB0734	NMB0966	Hypothetical protein; Identified by Glimmer2; putative.	Para-aminobenzoate synthase glutamine amidotransferase component II; Identified by similarity to EGAD:15630; match to protein family HMM PF00117; match to protein family HMM TIGR00566.	0.800
NMB0734	pheA	NMB0734	NMB0446	Hypothetical protein; Identified by Glimmer2; putative.	Chorismate mutase/prephenate dehydratase; Identified by similarity to GP:4105530; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01807.	0.889
NMB0734	trpE	NMB0734	NMB1021	Hypothetical protein; Identified by Glimmer2; putative.	Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]	0.812
NMB0734	tyrB	NMB0734	NMB1678	Hypothetical protein; Identified by Glimmer2; putative.	Aromatic-amino-acid aminotransferase; Identified by similarity to SP:P74861; match to protein family HMM PF00155.	0.800
NMB0734	ubiA	NMB0734	NMB0735	Hypothetical protein; Identified by Glimmer2; putative.	4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.	0.993
NMB1565	NMB0734	NMB1565	NMB0734	Hypothetical protein; Identified by Glimmer2; putative.	Hypothetical protein; Identified by Glimmer2; putative.	0.760
aroC	NMB0734	NMB1680	NMB0734	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Hypothetical protein; Identified by Glimmer2; putative.	0.800
aroC	hisC	NMB1680	NMB1582	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Histidinol-phosphate aminotransferase; Identified by similarity to EGAD:156515; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.683
aroC	pabA	NMB1680	NMB0966	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Para-aminobenzoate synthase glutamine amidotransferase component II; Identified by similarity to EGAD:15630; match to protein family HMM PF00117; match to protein family HMM TIGR00566.	0.946
aroC	pheA	NMB1680	NMB0446	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Chorismate mutase/prephenate dehydratase; Identified by similarity to GP:4105530; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01807.	0.986
aroC	trpE	NMB1680	NMB1021	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]	0.955
aroC	tyrB	NMB1680	NMB1678	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	Aromatic-amino-acid aminotransferase; Identified by similarity to SP:P74861; match to protein family HMM PF00155.	0.547
aspC	NMB0734	NMB0540	NMB0734	Aspartate aminotransferase; Identified by similarity to EGAD:28598; match to protein family HMM PF00155.	Hypothetical protein; Identified by Glimmer2; putative.	0.800
aspC	hisC	NMB0540	NMB1582	Aspartate aminotransferase; Identified by similarity to EGAD:28598; match to protein family HMM PF00155.	Histidinol-phosphate aminotransferase; Identified by similarity to EGAD:156515; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.911
aspC	pheA	NMB0540	NMB0446	Aspartate aminotransferase; Identified by similarity to EGAD:28598; match to protein family HMM PF00155.	Chorismate mutase/prephenate dehydratase; Identified by similarity to GP:4105530; match to protein family HMM PF00800; match to protein family HMM PF01817; match to protein family HMM PF01842; match to protein family HMM TIGR01807.	0.964