NMB0741 protein (Neisseria meningitidis) - STRING interaction network

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NMB0741

Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (479 aa)

Predicted Functional Partners:

NMB1828

0.800

NMB1349

0.699

lptA

0.605

NMB0779

0.587

NMB0438

0.572

trmA

0.537

FxsA

0.505

NMB1440

0.487

NMB1681

0.481

NMB0853

0.469

Your Current Organism:

Neisseria meningitidis

NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FxsA	NMB0741	NMB0730	NMB0741	Hypothetical protein; Identified by Glimmer2; putative.	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	0.505
FxsA	NMB0779	NMB0730	NMB0779	Hypothetical protein; Identified by Glimmer2; putative.	Hypothetical protein; Identified by Glimmer2; putative.	0.592
FxsA	NMB1349	NMB0730	NMB1349	Hypothetical protein; Identified by Glimmer2; putative.	Hypothetical protein; Identified by Glimmer2; putative.	0.707
FxsA	NMB1440	NMB0730	NMB1440	Hypothetical protein; Identified by Glimmer2; putative.	Hypothetical protein; Identified by Glimmer2; putative.	0.581
FxsA	NMB1681	NMB0730	NMB1681	Hypothetical protein; Identified by Glimmer2; putative.	Hypothetical protein; Identified by Glimmer2; putative.	0.766
NMB0438	NMB0741	NMB0438	NMB0741	Hypothetical protein; Identified by Glimmer2; putative.	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	0.572
NMB0438	NMB1349	NMB0438	NMB1349	Hypothetical protein; Identified by Glimmer2; putative.	Hypothetical protein; Identified by Glimmer2; putative.	0.434
NMB0438	NMB1440	NMB0438	NMB1440	Hypothetical protein; Identified by Glimmer2; putative.	Hypothetical protein; Identified by Glimmer2; putative.	0.482
NMB0741	FxsA	NMB0741	NMB0730	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	Hypothetical protein; Identified by Glimmer2; putative.	0.505
NMB0741	NMB0438	NMB0741	NMB0438	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	Hypothetical protein; Identified by Glimmer2; putative.	0.572
NMB0741	NMB0779	NMB0741	NMB0779	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	Hypothetical protein; Identified by Glimmer2; putative.	0.587
NMB0741	NMB0853	NMB0741	NMB0853	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	Conserved hypothetical protein; Identified by similarity to EGAD:90623; match to protein family HMM PF07719.	0.469
NMB0741	NMB1349	NMB0741	NMB1349	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	Hypothetical protein; Identified by Glimmer2; putative.	0.699
NMB0741	NMB1440	NMB0741	NMB1440	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	Hypothetical protein; Identified by Glimmer2; putative.	0.487
NMB0741	NMB1681	NMB0741	NMB1681	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	Hypothetical protein; Identified by Glimmer2; putative.	0.481
NMB0741	NMB1828	NMB0741	NMB1828	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	Conserved hypothetical protein; Identified by similarity to GP:2738251; match to protein family HMM PF00756.	0.800
NMB0741	lptA	NMB0741	NMB0355	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.	0.605
NMB0741	trmA	NMB0741	NMB1679	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).	0.537
NMB0779	FxsA	NMB0779	NMB0730	Hypothetical protein; Identified by Glimmer2; putative.	Hypothetical protein; Identified by Glimmer2; putative.	0.592
NMB0779	NMB0741	NMB0779	NMB0741	Hypothetical protein; Identified by Glimmer2; putative.	Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.	0.587

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