Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NMB0747Conserved hypothetical protein; Identified by similarity to EGAD:108409; match to protein family HMM PF06962. (188 aa)    
Predicted Functional Partners:
NMB0749
Penicillin-binding protein 4; Identified by similarity to EGAD:8088; match to protein family HMM PF00768; Belongs to the peptidase S11 family.
     
 0.851
NMB0746
Conserved hypothetical protein; Identified by similarity to EGAD:36863; match to protein family HMM PF04247.
  
    0.760
hfq
Host factor-I; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
 
  
 0.719
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
     
 0.692
hflX
GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
      
 0.679
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine-pyrophosphokinase; Identified by similarity to EGAD:27899; match to protein family HMM PF01288; match to protein family HMM TIGR01498.
  
    0.644
NMB0994
Identified by similarity to EGAD:38335; match to protein family HMM PF02771.
   
    0.426
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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