Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NMB0764Conserved hypothetical protein; Identified by similarity to GP:3413203; match to protein family HMM PF00892. (301 aa)    
Predicted Functional Partners:
NMB1274
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.545
NMB1018
Conserved hypothetical protein; Identified by similarity to EGAD:48492; match to protein family HMM PF00583.
  
    0.541
NMB0698
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.518
pilB
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
 
     0.485
NMB1269
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.485
NMB1028
Conserved hypothetical protein; Identified by similarity to EGAD:28370.
  
     0.473
NMB0021
pilS cassette; Identified by similarity to EGAD:11801.
  
     0.468
NMB0019
pilS cassette; Identified by similarity to GP:349528; match to protein family HMM PF00114.
  
     0.461
hsf
Adhesin; Involved in adhesion of capsulated meningococci to host epithelial cells. Interacts with laminin and heparan sulfate, promoting the adherence to the extracellular matrix (ECM) components.
  
     0.445
NMB0023
pilS cassette; Identified by similarity to EGAD:11802; match to protein family HMM PF00114.
  
     0.442
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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