node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NMB0527 | folE2 | NMB0527 | NMB0803 | Putative 6-pyruvoyl tetrahydrobiopterin synthase; Identified by similarity to EGAD:28193; match to protein family HMM PF01242. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.917 |
NMB0527 | ntpA | NMB0527 | NMB0642 | Putative 6-pyruvoyl tetrahydrobiopterin synthase; Identified by similarity to EGAD:28193; match to protein family HMM PF01242. | dATP pyrophosphohydrolase; Identified by similarity to EGAD:24131; match to protein family HMM PF00293. | 0.900 |
NMB1263 | folE2 | NMB1263 | NMB0803 | CobW-related protein; Identified by similarity to EGAD:156097; match to protein family HMM PF02492; match to protein family HMM PF07683. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.554 |
folE2 | NMB0527 | NMB0803 | NMB0527 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Putative 6-pyruvoyl tetrahydrobiopterin synthase; Identified by similarity to EGAD:28193; match to protein family HMM PF01242. | 0.917 |
folE2 | NMB1263 | NMB0803 | NMB1263 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | CobW-related protein; Identified by similarity to EGAD:156097; match to protein family HMM PF02492; match to protein family HMM PF07683. | 0.554 |
folE2 | folK | NMB0803 | NMB0745 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine-pyrophosphokinase; Identified by similarity to EGAD:27899; match to protein family HMM PF01288; match to protein family HMM TIGR01498. | 0.882 |
folE2 | ndk | NMB0803 | NMB1307 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.800 |
folE2 | ntpA | NMB0803 | NMB0642 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | dATP pyrophosphohydrolase; Identified by similarity to EGAD:24131; match to protein family HMM PF00293. | 0.900 |
folE2 | pykA | NMB0803 | NMB0089 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Pyruvate kinase II; Identified by similarity to EGAD:21471; match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.809 |
folE2 | relA | NMB0803 | NMB1735 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.800 |
folE2 | ribA | NMB0803 | NMB1254 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.900 |
folE2 | ribA/B | NMB0803 | NMB1256 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.902 |
folE2 | spoT | NMB0803 | NMB1659 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Guanosine-3`,5`-bis(diphosphate) 3`-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.800 |
folK | folE2 | NMB0745 | NMB0803 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine-pyrophosphokinase; Identified by similarity to EGAD:27899; match to protein family HMM PF01288; match to protein family HMM TIGR01498. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.882 |
folK | ribA/B | NMB0745 | NMB1256 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine-pyrophosphokinase; Identified by similarity to EGAD:27899; match to protein family HMM PF01288; match to protein family HMM TIGR01498. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.605 |
ndk | folE2 | NMB1307 | NMB0803 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
ndk | pykA | NMB1307 | NMB0089 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Pyruvate kinase II; Identified by similarity to EGAD:21471; match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.905 |
ndk | relA | NMB1307 | NMB1735 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.907 |
ndk | ribA | NMB1307 | NMB1254 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.820 |
ndk | ribA/B | NMB1307 | NMB1256 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.892 |