Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NMB0853Conserved hypothetical protein; Identified by similarity to EGAD:90623; match to protein family HMM PF07719. (209 aa)    
Predicted Functional Partners:
hisS-2
histidyl-tRNA synthetase; Identified by similarity to GP:1573338; match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442.
  
    0.955
NMB0778
Putative uroporphyrin-III C-methyltransferase HemX; Identified by similarity to EGAD:22018; match to protein family HMM PF04375.
  
    0.709
NMB0779
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.672
der
Essential GTPase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
    0.620
secE
Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
    0.567
NMB0855
Putative bacteriocin resistance protein; Identified by similarity to GP:2909665; match to protein family HMM PF03412.
       0.536
NMB0667
Hypothetical protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.523
gshA
Glutamate--cysteine ligase; Identified by similarity to EGAD:41093; match to protein family HMM TIGR02049.
  
    0.505
NMB1570
Conserved hypothetical protein; Identified by similarity to EGAD:24062; match to protein family HMM PF03739.
  
     0.495
NMB1440
Hypothetical protein; Identified by Glimmer2; putative.
 
    0.475
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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