Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NMB0868Conserved hypothetical protein; Identified by similarity to EGAD:162676. (213 aa)    
Predicted Functional Partners:
speE-2
Hypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
    0.688
NMB0867
YabO/YceC/SfhB family protein; Identified by similarity to EGAD:161394; match to protein family HMM PF00849.
  
   
 0.585
gshA
Glutamate--cysteine ligase; Identified by similarity to EGAD:41093; match to protein family HMM TIGR02049.
  
     0.530
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
  
  
 0.497
NMB0665
Oxygen-independent coprophorphyrinogen III oxidase family protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
   
    0.460
NMB1515
Putative transporter; Identified by similarity to EGAD:36624; match to protein family HMM PF07690.
  
     0.456
NMB0105
PhnO-related protein; Identified by similarity to EGAD:108538; match to protein family HMM PF00583.
  
     0.401
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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