Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pemIpemI protein; Identified by similarity to EGAD:24580; match to protein family HMM PF04014. (78 aa)    
Predicted Functional Partners:
pemK
pemK protein; Identified by similarity to GP:2688953.
  
 
 0.987
NMB2038
PemK-related protein; Identified by similarity to EGAD:108126; match to protein family HMM PF02452.
  
 
 0.709
NMB1635
Hypothetical protein; Identified by Glimmer2; putative.
   
    0.638
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
   
    0.513
NMB1333
Conserved hypothetical protein; Identified by similarity to EGAD:27923; match to protein family HMM PF01551.
      
 0.487
NMB2001
Conserved hypothetical protein; Identified by similarity to EGAD:91561; match to protein family HMM PF00877.
      
 0.487
NMB0915
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.475
NMB1749
Conserved hypothetical protein; Identified by similarity to GP:3402502; match to protein family HMM PF05707.
   
    0.472
NMB0916
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.458
NMB1096
Conserved hypothetical protein; Identified by similarity to EGAD:28498; match to protein family HMM PF04233; match to protein family HMM TIGR01641.
   
    0.450
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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