Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
icdIsocitrate dehydrogenase, NADP-dependent, monomeric type; Identified by similarity to EGAD:40125; match to protein family HMM PF03971; match to protein family HMM TIGR00178; Belongs to the monomeric-type IDH family. (741 aa)    
Predicted Functional Partners:
acnB
Aconitate hydratase 2; Identified by similarity to EGAD:8034; match to protein family HMM PF00330; match to protein family HMM PF06434; match to protein family HMM TIGR00117; Belongs to the aconitase/IPM isomerase family.
   
 
 0.946
sucA
2-oxoglutarate dehydrogenase, E1 component; Identified by similarity to EGAD:102382; match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239.
   
 
 0.915
gdhA
Glutamate dehydrogenase, NADP-specific; Identified by similarity to GP:146126; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.852
gluD
Glutamate dehydrogenase, NAD-specific; Identified by similarity to EGAD:20751; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.836
argH
Argininosuccinate lyase; Identified by similarity to EGAD:49512; match to protein family HMM PF00206; match to protein family HMM TIGR00838.
     
 0.825
purB
Adenylosuccinate lyase; Identified by similarity to EGAD:14517; match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  0.821
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
  0.800
aspC
Aspartate aminotransferase; Identified by similarity to EGAD:28598; match to protein family HMM PF00155.
     
  0.800
aspA
Aspartate ammonia-lyase; Identified by similarity to GP:41008; match to protein family HMM PF00206; match to protein family HMM TIGR00839.
     
  0.800
NMB1353
Identified by similarity to EGAD:91347; match to protein family HMM PF00171.
     
  0.800
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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