| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceF | lpdA2 | NMB1342 | NMB1344 | Pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.992 |
| aceF | prpB | NMB1342 | NMB0430 | Pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Putative carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.800 |
| aceF | sdhA | NMB1342 | NMB0950 | Pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, flavoprotein subunit; Identified by similarity to GP:3273345; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.545 |
| aceF | sdhB | NMB1342 | NMB0951 | Pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, iron-sulfur protein; Identified by similarity to EGAD:19944; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.569 |
| aceF | sdhC | NMB1342 | NMB0948 | Pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, cytochrome b556 subunit; Identified by similarity to GP:3273343; match to protein family HMM PF01127. | 0.444 |
| aceF | sucA | NMB1342 | NMB0955 | Pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase, E1 component; Identified by similarity to EGAD:102382; match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239. | 0.974 |
| aceF | sucC | NMB1342 | NMB0959 | Pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.967 |
| aceF | sucD | NMB1342 | NMB0960 | Pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.950 |
| lpdA2 | aceF | NMB1344 | NMB1342 | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | Pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.992 |
| lpdA2 | sdhA | NMB1344 | NMB0950 | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | Succinate dehydrogenase, flavoprotein subunit; Identified by similarity to GP:3273345; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.939 |
| lpdA2 | sdhB | NMB1344 | NMB0951 | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | Succinate dehydrogenase, iron-sulfur protein; Identified by similarity to EGAD:19944; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.931 |
| lpdA2 | sdhC | NMB1344 | NMB0948 | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | Succinate dehydrogenase, cytochrome b556 subunit; Identified by similarity to GP:3273343; match to protein family HMM PF01127. | 0.813 |
| lpdA2 | sdhD | NMB1344 | NMB0949 | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | Succinate dehydrogenase, hydrophobic membrane anchor protein; Identified by similarity to GP:3273344. | 0.713 |
| lpdA2 | sucA | NMB1344 | NMB0955 | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 2-oxoglutarate dehydrogenase, E1 component; Identified by similarity to EGAD:102382; match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239. | 0.999 |
| lpdA2 | sucB | NMB1344 | NMB0956 | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.990 |
| lpdA2 | sucC | NMB1344 | NMB0959 | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.982 |
| lpdA2 | sucD | NMB1344 | NMB0960 | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.921 |
| prpB | aceF | NMB0430 | NMB1342 | Putative carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | Pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.800 |
| prpB | sucC | NMB0430 | NMB0959 | Putative carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.927 |
| prpB | sucD | NMB0430 | NMB0960 | Putative carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.920 |
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