STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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hsfAdhesin; Involved in adhesion of capsulated meningococci to host epithelial cells. Interacts with laminin and heparan sulfate, promoting the adherence to the extracellular matrix (ECM) components. (591 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.
      
 0.785
opc
Class 5 outer membrane protein; Identified by similarity to GP:1177565; match to protein family HMM PF07239.
      
 0.774
hap
Adhesion and penetration protein; Identified by similarity to GP:1408569; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414.
      
 0.774
mlp
Lipoprotein; Identified by similarity to EGAD:40759; match to protein family HMM PF04355.
 
   
 0.766
NMB0313
Conserved hypothetical protein; Identified by similarity to GP:3523136; match to protein family HMM PF04575; match to protein family HMM PF07719.
  
     0.757
lbpA
Lactoferrin-binding protein A; Unknown. May be an iron-siderophore receptor.
  
     0.721
lgtB
lacto-N-neotetraose biosynthesis glycosyl transferase LgtB; Adds the second galactose to the lacto-N-tetraose chain in lipooligosaccharide (LOS).
  
     0.695
tbp1
Transferrin-binding protein 1; Acts as a transferrin receptor and is required for transferrin utilization; Belongs to the TonB-dependent receptor family.
  
     0.693
NMB1634
Conserved hypothetical protein; Identified by similarity to GP:3402495; match to protein family HMM PF02486.
  
     0.692
NMB1028
Conserved hypothetical protein; Identified by similarity to EGAD:28370.
  
    0.666
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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