Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
NMB1020Hypothetical protein; Identified by Glimmer2; putative. (181 aa)    
Predicted Functional Partners:
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
       0.774
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
       0.773
NMB1580
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.760
NMB1551
Conserved hypothetical protein; Identified by similarity to GP:3402502; match to protein family HMM PF05707.
  
     0.733
NMB1626
Conserved hypothetical protein; Identified by similarity to GP:3402502; match to protein family HMM PF05707.
  
     0.733
NMB0341
tspA protein; Identified by similarity to GP:3413497; match to protein family HMM PF01476.
  
     0.728
lgtB
lacto-N-neotetraose biosynthesis glycosyl transferase LgtB; Adds the second galactose to the lacto-N-tetraose chain in lipooligosaccharide (LOS).
  
     0.713
NMB1818
Putative lipopolysaccharide biosynthesis protein; Identified by similarity to EGAD:165571; match to protein family HMM PF01943.
  
    0.710
NMB1040
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.708
NMB1280
Very long chain acyl-CoA dehydrogenase-related protein; Identified by similarity to EGAD:60787; match to protein family HMM PF00441.
  
     0.706
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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