STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NMB1024Conserved hypothetical protein; Identified by similarity to EGAD:36674; match to protein family HMM PF01571; Belongs to the GcvT family. (288 aa)    
Predicted Functional Partners:
NMB1025
Conserved hypothetical protein; Identified by similarity to EGAD:132011; match to protein family HMM PF01042.
  
    0.720
NMB1381
HesB/YadR/YfhF family protein; Identified by similarity to EGAD:91885; match to protein family HMM PF01521; match to protein family HMM TIGR00049; match to protein family HMM TIGR02011; Belongs to the HesB/IscA family.
  
 
 0.564
erpA
Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters.
  
 
 0.560
NMB1026
Conserved hypothetical protein; Identified by similarity to EGAD:91370; match to protein family HMM PF04073; match to protein family HMM TIGR00011; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
  
    0.555
ttcA
Conserved hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. Belongs to the TtcA family.
       0.538
NMB1018
Conserved hypothetical protein; Identified by similarity to EGAD:48492; match to protein family HMM PF00583.
 
     0.521
cysG-1
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
     
 0.496
cysG-2
Siroheme synthase; Identified by similarity to EGAD:142433; match to protein family HMM PF00590; match to protein family HMM TIGR01469; match to protein family HMM TIGR01470.
     
 0.496
NMB1027
dnaJ protein, truncation; Identified by similarity to EGAD:48808.
  
    0.466
NMB1028
Conserved hypothetical protein; Identified by similarity to EGAD:28370.
  
    0.457
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.