Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
NMB1137Conserved hypothetical protein; Identified by similarity to GP:3046317; match to protein family HMM PF04384. (65 aa)    
Predicted Functional Partners:
fdx-1
Ferredoxin, 2Fe-2S type; Identified by similarity to EGAD:19142; match to protein family HMM PF00111; match to protein family HMM TIGR02007.
 
  
 0.928
fdx-2
Ferredoxin, 2Fe-2S type; Identified by similarity to EGAD:19142; match to protein family HMM PF00111; match to protein family HMM TIGR02007.
 
  
 0.901
hscB
Chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
 
  
 0.865
NMB1136
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.775
hscA-1
Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
 
  
 0.581
nifS
nifS protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
 
 0.560
NMB1135
Hypothetical protein; Identified by Glimmer2; putative.
       0.536
NMB1380
nifU protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 
 0.513
NMB1381
HesB/YadR/YfhF family protein; Identified by similarity to EGAD:91885; match to protein family HMM PF01521; match to protein family HMM TIGR00049; match to protein family HMM TIGR02011; Belongs to the HesB/IscA family.
 
  
 0.494
hscA-2
Chaperone protein HscA; Identified by similarity to EGAD:13274; match to protein family HMM PF00012; match to protein family HMM TIGR01991.
 
  
 0.463
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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