STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tilS-2tRNA(Ile)-lysidine synthetase; Identified by similarity to EGAD:90825; match to protein family HMM PF01171; match to protein family HMM TIGR02432; match to protein family HMM TIGR02433. (426 aa)    
Predicted Functional Partners:
birA/coaX
BirA protein/Bvg accessory factor; Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins; In the C-terminal section; belongs to the type III pantothenate kinase family.
 
    0.557
accA-2
acetyl-CoA carboxylase, carboxyl transferase alpha subunit; Identified by similarity to EGAD:21130; match to protein family HMM PF03255; match to protein family HMM TIGR00513.
       0.554
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.498
cdsA
Phosphatidate cytidylyltransferase; Identified by similarity to EGAD:46780; match to protein family HMM PF01148; Belongs to the CDS family.
 
     0.449
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.441
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.434
NMB1179
RNA methyltransferase, TrmH family; Identified by similarity to EGAD:107730; match to protein family HMM PF00588.
  
    0.429
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.428
NMB0341
tspA protein; Identified by similarity to GP:3413497; match to protein family HMM PF01476.
  
     0.402
pheT
phenylalanyl-tRNA synthetase, beta chain; Identified by similarity to EGAD:16045; match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
   
 0.401
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.