node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NMB1215 | NMB1218 | NMB1215 | NMB1218 | Hypothetical protein; Identified by Glimmer2; putative. | Conserved hypothetical protein; Identified by similarity to EGAD:17261; match to protein family HMM PF04359; Belongs to the UPF0250 family. | 0.455 |
NMB1215 | lipA-2 | NMB1215 | NMB1216 | Hypothetical protein; Identified by Glimmer2; putative. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.457 |
NMB1215 | lipB-2 | NMB1215 | NMB1217 | Hypothetical protein; Identified by Glimmer2; putative. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.452 |
NMB1218 | NMB1215 | NMB1218 | NMB1215 | Conserved hypothetical protein; Identified by similarity to EGAD:17261; match to protein family HMM PF04359; Belongs to the UPF0250 family. | Hypothetical protein; Identified by Glimmer2; putative. | 0.455 |
NMB1218 | NMB1219 | NMB1218 | NMB1219 | Conserved hypothetical protein; Identified by similarity to EGAD:17261; match to protein family HMM PF04359; Belongs to the UPF0250 family. | Putative transporter; Identified by similarity to EGAD:107342; match to protein family HMM PF01594. | 0.504 |
NMB1218 | lipA-2 | NMB1218 | NMB1216 | Conserved hypothetical protein; Identified by similarity to EGAD:17261; match to protein family HMM PF04359; Belongs to the UPF0250 family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.846 |
NMB1218 | lipB-2 | NMB1218 | NMB1217 | Conserved hypothetical protein; Identified by similarity to EGAD:17261; match to protein family HMM PF04359; Belongs to the UPF0250 family. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.875 |
NMB1219 | NMB1218 | NMB1219 | NMB1218 | Putative transporter; Identified by similarity to EGAD:107342; match to protein family HMM PF01594. | Conserved hypothetical protein; Identified by similarity to EGAD:17261; match to protein family HMM PF04359; Belongs to the UPF0250 family. | 0.504 |
NMB1219 | lipA-2 | NMB1219 | NMB1216 | Putative transporter; Identified by similarity to EGAD:107342; match to protein family HMM PF01594. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.507 |
NMB1219 | lipB-2 | NMB1219 | NMB1217 | Putative transporter; Identified by similarity to EGAD:107342; match to protein family HMM PF01594. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.511 |
NMB1846 | guaA | NMB1846 | NMB1920 | Mrp/NBP35 family protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.519 |
NMB1846 | lipA-2 | NMB1846 | NMB1216 | Mrp/NBP35 family protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.423 |
crcB | lipA-2 | NMB1065 | NMB1216 | crcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.470 |
gcvH | lipA-2 | NMB0575 | NMB1216 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.924 |
gcvH | lipB-2 | NMB0575 | NMB1217 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.961 |
gcvH | lpdA2 | NMB0575 | NMB1344 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.994 |
gcvH | sucB | NMB0575 | NMB0956 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.693 |
guaA | NMB1846 | NMB1920 | NMB1846 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Mrp/NBP35 family protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.519 |
guaA | lipA-2 | NMB1920 | NMB1216 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.538 |
guaA | lpdA2 | NMB1920 | NMB1344 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Pyruvate dehydrogenase, E3 component, lipoamide dehydrogenase; Identified by similarity to GP:1006678; match to protein family HMM PF00070; match to protein family HMM PF00364; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.538 |