Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glxKConserved hypothetical protein; Identified by similarity to EGAD:30688; match to protein family HMM PF02595; match to protein family HMM TIGR00045. (371 aa)    
Predicted Functional Partners:
hprA
Glycerate dehydrogenase; Identified by similarity to EGAD:28541; match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.925
gpm
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
     
  0.900
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
      
 0.774
tadA
Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
    0.667
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
      
 0.571
avtA
Valine--pyruvate aminotransferase; Identified by similarity to GP:3299892.
      
 0.567
gntP
Gluconate permease; Identified by similarity to EGAD:36585; match to protein family HMM PF02447; match to protein family HMM TIGR00791.
 
  
 0.548
NMB1269
Hypothetical protein; Identified by Glimmer2; putative.
       0.511
NMB1267
Low molecular weight protein tyrosine-phosphatase; Identified by similarity to EGAD:107998; match to protein family HMM PF01451; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
       0.499
mutY
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
      
 0.448
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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