Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rsuARibosomal small subunit pseudouridine synthase A; Identified by similarity to EGAD:165416; match to protein family HMM PF00849; match to protein family HMM TIGR00093; Belongs to the pseudouridine synthase RsuA family. (230 aa)    
Predicted Functional Partners:
NMB1076
DnaA-related protein; Identified by similarity to EGAD:91757; Belongs to the DnaA family.
      
 0.774
NMB1024
Conserved hypothetical protein; Identified by similarity to EGAD:36674; match to protein family HMM PF01571; Belongs to the GcvT family.
      
 0.771
efp
Elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
 
  
 0.763
der
Essential GTPase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.762
NMB1297
Membrane-bound lytic murein transglycosylase D; Identified by similarity to EGAD:8903; match to protein family HMM PF01464; match to protein family HMM PF01476; match to protein family HMM PF06474.
  
    0.589
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).
      
 0.523
NMB0739
Conserved hypothetical protein; Identified by similarity to EGAD:108433; match to protein family HMM PF01926; match to protein family HMM PF04079; match to protein family HMM TIGR00650.
  
  
 0.493
cmk
Cytidylate kinase; Identified by similarity to EGAD:10189; match to protein family HMM PF02224; match to protein family HMM TIGR00017.
  
  
 0.477
exoA
Exodeoxyribonuclease; Identified by similarity to EGAD:19899; match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633.
  
    0.473
xthA
Exodeoxyribonuclease III; Identified by similarity to EGAD:104607; match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633.
   
    0.467
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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