Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prcCarboxy-terminal peptidase; Identified by similarity to GP:555748; match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; Belongs to the peptidase S41A family. (494 aa)    
Predicted Functional Partners:
dgkA
Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
      
 0.774
NMB1333
Conserved hypothetical protein; Identified by similarity to EGAD:27923; match to protein family HMM PF01551.
  
  
 0.756
NMB0872
Conserved hypothetical protein; Identified by similarity to EGAD:30939; match to protein family HMM PF07719.
  
   0.727
clpA
ATP-dependent Clp protease, ATP-binding subunit ClpA; Identified by similarity to EGAD:17776; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; Belongs to the ClpA/ClpB family.
 
  
 0.699
clpP
ATP-dependent Clp protease, proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.560
NMB0183
Conserved hypothetical protein; Identified by similarity to EGAD:8229; match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054; Belongs to the peptidase M50B family.
 
  
 0.515
pilB
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
 
   0.477
NMB1405
FrpA/C-related protein; Identified by similarity to EGAD:22554.
   
   0.476
NMB1565
Hypothetical protein; Identified by Glimmer2; putative.
   
   0.476
NMB1870
Hypothetical protein; Identified by Glimmer2; putative.
   
   0.476
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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