Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glkGlucokinase; Identified by similarity to EGAD:90183; match to protein family HMM PF02685; match to protein family HMM TIGR00749; Belongs to the bacterial glucokinase family. (328 aa)    
Predicted Functional Partners:
NMB1389
RpiR/YebK/YfhH family protein; Identified by similarity to EGAD:30099; match to protein family HMM PF01380; match to protein family HMM PF01418.
  
 0.960
pgl
Oxidoreductase, Sol/DevB family; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
  
 0.960
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 
 0.957
pgi-2
Glucose-6-phosphate isomerase; Identified by similarity to EGAD:90386; match to protein family HMM PF00342.
    
 0.947
pgm
Phosphoglucomutase; This enzyme participates in both the breakdown and synthesis of glucose; Belongs to the phosphohexose mutase family.
     
 0.935
eda
4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase; Identified by similarity to EGAD:32697; match to protein family HMM PF01081; match to protein family HMM TIGR01182.
 
 
 0.923
galM
Aldose 1-epimerase; Identified by similarity to EGAD:7305; match to protein family HMM PF01263.
   
 
 0.922
pgi-1
Glucose-6-phosphate isomerase; Identified by similarity to EGAD:7650; match to protein family HMM PF00342.
    
 0.914
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
    
 0.874
tktA
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
    
 0.874
Your Current Organism:
Neisseria meningitidis
NCBI taxonomy Id: 122586
Other names: N. meningitidis MC58, Neisseria meningitidis MC58, Neisseria meningitidis serogroup B strain MC58
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